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对44例T2DM行动态血糖监测系统(CGMS)、糖化血红蛋白(HbA1c)及CRP检查,并以血糖标准差(SDBG)为依据分组研究2型糖尿病(T2DM)血糖波动与CRP之间的相关性。结果所有T2DM与正常对照组之间平均血糖、HbA1c、hs-CRP差异有统计学意义(P<0.05);SDBG≤1.4mmol/L组与1.4mmol/L0.05),而两组hs-CRP差异存在统计学意义(P<0.05);在2.0mmol/L3.0mmol/L之间存在同样的结果;相关分析表明,在T2DM中hs-CRP与HbA1c相关,在HbA1 c相似的人群中,hs-CRP还与SDBG相关。结论:T2DM的hs-CRP不仅与平均血糖、HbA1c有关,而且与血糖的波动性有关。
CGMS, HbA1c and CRP were examined in 44 patients with T2DM. The correlation between blood glucose and type 2 diabetes mellitus (T2DM) was analyzed based on the standard deviation of blood glucose (SDBG). Results The mean blood glucose, HbA1c and hs-CRP between T2DM group and normal control group were significantly different (P <0.05); between SDBG≤1.4mmol / L group and 1.4mmol / L 0.05). The difference of hs-CRP between the two groups was statistically significant (P <0.05). In the group of 2.0 mmol / L SDBG≤3.0 mmol / L and SDBG > 3.0 mmol / L. The correlation analysis showed that hs-CRP was associated with HbA1c in T2DM, and hs-CRP was also associated with SDBG in HbA1c-like cohorts. Conclusion: The hs-CRP in T2DM is not only related to the average blood glucose and HbA1c, but also to the fluctuation of blood glucose.