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目的:对比分析静脉微量胰岛素滴注和微量泵皮下胰岛素持续给药在治疗酮症酸中毒之间的疗效。方法:将64例糖尿病酮症酸中毒患者分为静脉微量胰岛素滴注给药和微量泵皮下持续给药两组,对两组在治疗后控制血糖所需时间、胰岛素用量、糖尿病酮症酸中毒消失所需时间、低血糖的出现等指标间进行对照分析。结果:早期静脉通道胰岛素快速滴注给药有利于迅速降低血糖,后期微量泵持续给药在控制血糖、节省胰岛素用药量、缩短酮症酸中毒的消失时间等方面有明显优势。结论:两种给药方式在治疗酮症酸中毒的不同阶段各有优势,静脉通道胰岛素微量滴注存在给药准确性差、血糖控制效果欠佳等缺点,两种方法的合理配合使用会提高治疗效果。
OBJECTIVE: To compare and analyze the curative effect of intravenous micro-insulin instillation and continuous subcutaneous insulin pump in the treatment of ketoacidosis. Methods: Sixty-four patients with diabetic ketoacidosis were divided into intravenous micro-insulin infusion and continuous infusion with subcutaneous pump. The time required for blood glucose control, insulin dosage, diabetic ketoacidosis Disappear time, the occurrence of hypoglycemia and other indicators between the control analysis. Results: Rapid intravenous drip infusion of insulin in the early intravenous route was beneficial to rapidly reduce blood glucose, while continuous administration of the late micropump in the latter period had obvious advantages in controlling blood sugar, saving insulin dosage and shortening the disappearance time of ketoacidosis. Conclusion: The two modes of administration have different advantages in the treatment of ketoacidosis at different stages. Intravenous insulin instillation has some disadvantages such as poor accuracy of administration and poor blood sugar control. The combination of the two methods can improve the therapy effect.