论文部分内容阅读
分泌性中耳炎（ＯＭＥ）患者６７例８２侧耳血清β２ｍ及免疫球蛋白、补体、抗核抗体检测结果与对照组相比无差异（Ｐ＞０．０５）．中耳分泌物（ＭＥＥ）全部可测到β２ｍ，其值为１１．Ｏ７±４．４２ｕｇ／ｍｌ，明显高于自身血清２．３９６±０．７１ｕｇ／ｍｌ（Ｐ＜０．００１）．两者比值（Ｅ／Ｓ）为５．６２±２．８９，该值在双耳患ＯＭＥ时其两耳差异显著（Ｐ＜０．０５）．咽鼓管畅通与不畅通者无显著差异（Ｐ＞０．０５）；Ｅ／Ｓ值高者预后都欠佳。２１例耳ＭＥＥ细菌学检查均为阴性。根据临床免疫学研究结果认为ＯＭＥ是一种与局部免疫复合物有关的疾病，而咽鼓管机能障碍并非是唯一引起其发病的必要条件，但对延长其病理状态起着重要作用。
There was no significant difference in the β2m and immunoglobulin, complement and antinuclear antibodies in 67 patients with secretory otitis media (OME) compared with the control group (P> 0.05). Middle ear secretions (MEE) all measured β2m, the value of 11. O7 ± 4.42ug / ml, significantly higher than its own serum 2.396 ± 0.71ug / ml (P <0.001). The ratio (E / S) was 5.62 ± 2.89, which was significantly different between ears (P <0.05). Eustachian tube unblocked and no significant difference (P> 0.05); high E / S prognosis are poor. 21 cases of ear MEE bacteriological examination were negative. According to the results of clinical immunology, OME is considered as a disease associated with local immune complexes. Eustachian tube dysfunction is not the only condition that causes it, but it plays an important role in prolonging the pathological state.