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目的探讨长期接触低浓度ＴＮＴ的神经行为学效应及生物学监测指标。方法应用ＷＨＯ－ＮＣＴＢ测定接触ＴＮＴ工人的早期神经行为改变并收集工人班末尿，测定尿中２，６－二硝基－４－氨基甲苯（ＤＮＡＴ）的含量。结果（１）长期接触低浓度ＴＮＴ可影响神经行为。主要表现为惰性情绪增加，记忆及运动稳定性降低。（２）尿ＤＮＡＴ含量明显增加，与ＮＣＴＢ得分存在一定接触－效应关系。结论神经行为学测试可作为检测ＴＮＴ接触工人早期影响的检测指标。ＮＣＴＢ得分与尿ＤＮＡＴ含量间具有较好相关性，尿ＤＮＡＴ含量可以反映工人的接触水平
Objective To investigate the neurobehavioral effects and biological monitoring of long-term exposure to low concentrations of TNT. Methods WHO-NCTB was used to measure the early neurobehavioral changes in workers exposed to TNT and workers’ urine samples were collected to determine the urinary 2,6-dinitro-4-aminotoluene (DNAT) content. Results (1) Long-term exposure to low concentrations of TNT can affect neurological behavior. Mainly for the increase of inertia, memory and exercise stability decreased. (2) The urinary DNAT content increased obviously, and there was some contact-effect relationship with NCTB score. Conclusion Neurobehavioral testing can be used as a test to detect early effects of exposure to TNT workers. NCTB score and urine DNAT content has a good correlation between the urine DNAT content can reflect the level of workers exposure