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肠道易激综合征(IBS)的肠动力异常被认为是由于在交感神经过度亢进的基础上加上了付交感神经的作用所致。用β受体阻滞剂治疗IBS已有零星报告,但有关此种治疗的前瞻性试验尚无报道。本文即系噻吗心安治疗IBS的前瞻性双盲法研究的报告。无选择的80例近期诊断为IBS的患者接受此项研究,其中6例失去联系故经一个月以上观察的共74例。每人每日饮食中含30克纤维素,按照双盲法,随机分别予以药物或安慰剂口服。治疗组37例(女性20例,男性17例,平均年龄为26岁,病程平均1～2年),用β受体阻滞剂噻吗心安每次10毫克,每日三次。对照组37例(女性24例,男性13例,平均年龄24岁,病程平
Intestinal motility disorders of irritable bowel syndrome (IBS) are thought to result from the addition of the sympathetic role to sympathetic hyperactivity. There have been sporadic reports of IBS with beta-blockers, but no prospective trial of this treatment has been reported. This article is the Department of tetramethylpyrazolol treatment of IBS prospective double-blind study reported. Eighty patients with no recent history of IBS were enrolled in this study, of which six were lost and 74 were observed over a month. Each person daily diet contains 30 grams of cellulose, according to double-blind method, were randomized to receive oral drugs or placebo. The treatment group of 37 patients (20 women, 17 males, mean age 26 years, duration of an average of 1 to 2 years), with beta blockers timolol every 10 mg three times a day. Control group, 37 cases (24 females, 13 males, mean age 24 years, duration of disease