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目的:探讨七氟醚与丙泊酚在小儿麻醉维持中对脑氧代谢的影响。方法:随机选择201 3年5月~2014年5月我院择期手术的患儿78例,以双盲法分为对照组与研究组,每组各39例,对照组麻醉维持中应用丙泊酚,研究组麻醉维持中应用七氟醚,并回顾性分析不同药物在小儿麻醉维持中应用对脑氧代谢的影响。结果:两组患儿的手术时间、术中输液量、术中的HR、ECG、Sp02等指标比较差异不明显、无统计学意义(P>0.05);但应用七氟醚麻醉维持的研完组患儿脑氧代谢降低程度要优于应用丙泊酚麻醉维持的对照组,组间比较差异有统计学意义(P<0.05)。结论:七氟醚应用于小儿麻醉维持中时、对降低脑氧代谢的效果比较显著、值得优先选用。
Objective: To investigate the effects of sevoflurane and propofol on cerebral oxygen metabolism during pediatric anesthesia maintenance. Methods: From May 2013 to May 2014, 78 children with elective surgery in our hospital were randomly divided into control group and study group with 39 cases in each group by double-blind method. In control group, propofol Phenol and Sevoflurane in the Study Group for Anesthesia Maintenance. The effects of different drugs on cerebral oxygen metabolism in pediatric anesthesia maintenance were retrospectively analyzed. Results: There was no significant difference between the two groups in the operation time, intraoperative fluid infusion, intraoperative HR, ECG, Sp02 and other indicators (P> 0.05). However, the application of sevoflurane anesthesia The reduction of cerebral oxygen metabolism in children was better than that of the control group, which was maintained by propofol anesthesia. There was significant difference between the two groups (P <0.05). Conclusion: When sevoflurane is used in the maintenance of pediatric anesthesia, the effect of reducing cerebral oxygen metabolism is significant and it is worth to be chosen first.