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长期用神经阻滞剂的患者常有诸多神经内分泌副反应,Siever认为金刚胺能降低催乳素血浓度、治疗溢乳症。为进一步评价金刚胺对神经阻滞剂所致的神经内分泌副反应的疗效,作者选择10例长期服用神经阻滞剂、有神经内分泌副反应的住院精神分裂症患者,其中男6例,女4例,年龄24～40岁,病期3～20年,作为期7周的自身对照研究。研究期间患者继续服原应用的神经阻滞剂,剂量保持不变。其中6例服甲砜达嗪150～400mg/日;2例服氟哌啶醇,日量分别为10mg及40mg;服氯丙嗪1600mg/日及克塞平150mg/日各1例。抗巴金森氏征药
Long-term use of nerve blockers in patients often have many neuroendocrine side effects, Siever that amantadine can reduce prolactin blood concentration, treatment of galactorrhea. To further evaluate the efficacy of amantadine in neuroendocrine side effects caused by nerve blockers, the authors selected 10 patients with long-term use of nerve blockers, neuroendocrine side effects of hospitalized schizophrenia patients, including 6 males and 4 females Cases, aged 24 to 40 years, the disease period of 3 to 20 years, as a 7-week self-control study. During the study patients continue to use the original application of nerve blockers, the dose remained unchanged. Among them, 6 cases received methyl sulfadiazine 150 ~ 400mg / day; 2 cases received haloperidol, the daily doses were 10mg and 40mg; taking chlorpromazine 1600mg / day and quetiapine 150mg / day in each case. Anti-Parkinson’s drug