论文部分内容阅读
作者分析了253例急性白血病患者的骨髓嗜酸性粒细胞的质和量,其中13例患者的骨髓嗜酸性粒细胞分类增高,并有形态的异常改变,占5.14%,其中M2、M3、M4、M5和M6等都有不同程度的改变。当这一类有嗜酸性粒细胞异常的患者病情缓解时,其异常消失,复发时则又出现。作者结合有关文献,对其病因学进行了初步探讨。根据观察到的临床特点,作者认为将伴有骨髓嗜酸性粒细胞改变的急性白血病作为一个独立的临床亚型,对于急性白血病的分类分型、治疗、病程进展以及预后的判断,都具有重要的临床意义。
The authors analyzed the mass and quantity of bone marrow eosinophils in 253 patients with acute leukemia, of which 13 patients had increased classification of their bone marrow eosinophils with an abnormal change in morphology accounting for 5.14%, of which M2, M3, M4, M5 and M6, etc. have different degrees of change. When this type of eosinophils in patients with remission of the disease, the anomaly disappeared, relapse occurs again. The author combined with the relevant literature, the etiology of a preliminary study. Based on the observed clinical characteristics, the authors believe that the acute leukemia associated with bone marrow eosinophilia as an independent clinical subtype, the classification of acute leukemia, treatment, progression and prognosis of judgments, are important Clinical significance.