【摘 要】
：
Eukaryotic DNA is hierarchically packaged into chroma-tin to fit inside the nucleus. Dynamics of the chromatin structure plays a critical role in transcriptiona
【机 构】
：
Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
论文部分内容阅读
Eukaryotic DNA is hierarchically packaged into chroma-tin to fit inside the nucleus. Dynamics of the chromatin structure plays a critical role in transcriptional regulation and other biological processes that involve DNA, such as DNA replication and DNA repair. Many factors, including histone variants, histone modification, DNA methylation and the binding of non-histone architectural proteins regulate the structure of chromatin. Although the structure of nucleosomes, the fundamental repeating unit of chromatin, is clear, there is still much discussion on the higher-order levels of chromatin structure. Identifying the structural details and dynamics of higher-order chromatin fibers is therefore very important for understanding the organization and regulation of gene activities. Here, we review studies on the dynamics of chromatin higher-order structure and its relationship with gene transcription.
其他文献
Arabidopsis AtPRMT10 is a plant-specific type Ⅰ protein arginine methyltransferase that can asymmetrically dimethylate arginine 3 of histone H4 with auto-methy
microRNAs (miRNAs) are 20-24 nucleotide (nt) RNAs that regulate eukaryotic gene expression post-transcription-ally by the degradation or translational inhibitio
(括号内敖字依次为期和页码)综述播枣茶叶的固顾与前瞎……………………林学和(卜一2)论我国茶业发展中的肥料同题…………廖万有(1—32)闺北茶叶发展方向分析……南平迪区茶
Alzheimer’s disease (AD) pathogenesis is characterized by senile plaques in the brain and evidence of oxidative damage.Oxidative stress may precede plaque form
Morphogenesis and maturation of viral particles is an essential step of viral replication. An infectious herpes-viral particle has a multilayered architecture,
Polo-like kinase 1 (Plk1) is a key regulator of cell division in eukaryotic cells. In this short review, we briefly summarized the well-established functions mo
该品种是福建省农科院红萍中心育种组科研人员用小叶萍为母本,榕萍1号为父本种间有性杂交筛选培育的优良新品种。其主要优点:①个体大、繁殖快、产量比父母本及当家品种卡洲
莽山野柑(Citrus nobilis Lauriro)是一种珍贵的野生柑橘种质资源,利用GC-MS分析莽山野柑果皮挥发性物质发现其特征香气为p-月桂烯(β-myrcene)和芳樟醇氧化物(linalool oxid
冀红小豆3号是保定地区农科所由冀红小一号和日本小豆大纳言的杂交后代,经多年连续选育而成。1992年2月由河北省农作物品种审定委员会定名为冀红小豆3号。 该品种株型为半葡
Tyrosine aminotransferase (TAT) catalyzes the transami-nation of tyrosine and other aromatic amino acids. The enzyme is thought to play a role in tyrosinemia ty