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已知维生素D及其活性代谢物1,25-双羟维生素D_2(1,25(OH)_2D_3)对钙磷代谢有重要作用,但尚不知其对镁代谢的作用。本文给Vit D缺乏鼠一定量的1,25(OH)_2D_3和24,25—双羟维生素D_3(24,25(OH)_2D_3),观察对鼠镁代谢的影响。 选体重90～100g的雄鼠分别喂养,自由饮水和进食,食物中含(mg/100g)Ca=600,Mg=30,P=100及一种标准的无Vit D的维生素混合物。40天后可见鼠有佝偻病表现。再将鼠分为4组。Ⅰ
It is known that vitamin D and its active metabolite 1,25-dihydroxyvitamin D_2 (1,25 (OH) _2D_3) play an important role in the metabolism of calcium and phosphorus, but its effect on the metabolism of magnesium is unknown. In this paper, Vit D lacking rats a certain amount of 1,25 (OH) _2D_3 and 24,25-dihydroxyvitamin D_3 (24,25 (OH) _2D_3) to observe the impact of magnesium metabolism in mice. Male rats weighing 90-100 g were fed with free access to water and food containing (mg / 100 g) Ca = 600, Mg = 30, P = 100, and a standard vitamin D-free mixture. Forty days later, rats showed rickets. Rats were divided into 4 groups. Ⅰ