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129例晚期前列腺癌,放免法测定血清前列腺特异性原(PSA)和前列腺酸性磷酸酶(PAP),其阳性率分别为92.1%和69.7%PSA和PAP值与临床分期相关,是监测疾病转归有价值的指标,该组分析内分泌治疗着重研究国产LHRH类似物的疗效,初步探讨双侧睾丸切除加flutamide作为完全性维激素阻断治疗的疗效。作者在内分泌治疗基础上采取姑息性耻骨后前列腺摘除术和经尿道前列腺切除术解除下尿道梗阻,以及尿道改道术解除上尿路梗阻的方法来提高病人存活期。
129 cases of advanced prostate cancer, serum PSA and prostatic acid phosphatase (PAP) were detected by radioimmunoassay, the positive rates were 92.1% and 69.7%, respectively. The PSA and PAP values were correlated with clinical stage and were Monitoring the prognosis of disease valuable indicators, the group analysis of endocrine therapy focuses on the efficacy of domestic LHRH analogues, preliminary discussion of bilateral orchidectomy plus flutamide as a complete treatment of vitamin Hormones curative effect. On the basis of endocrine therapy, the author adopts palliative retropubic prostatectomy and transurethral resection of prostate to remove lower urinary tract obstruction, and urethral diversion to relieve upper urinary tract obstruction to improve patient survival.