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目的分析针对性健康教育配合干扰素雾化吸入用于小儿手足口病的临床疗效。方法将小儿手足口病患儿224例随机分为试验组和对照组各112例。试验组在给予针对性健康教育及基础治疗的同时配合重组人干扰素α-2b雾化吸入;对照组在给予针对性健康教育及基础治疗的同时配合利巴韦林、喜炎平治疗。统计2组患者退热时间、皮疹消退时间、住院时间等,评价2组治疗效果。结果试验组患者退热时间、皮疹消退时间及住院时间均显著短于对照组,总有效率为91.96%明显高于对照组的61.61%,差异均有统计学意义(P<0.05)。结论重组人干扰素α-2b配合针对性健康教育和基础治疗小儿手足口病患儿相关症状消失快、体征短时间内明显好转,值得临床推广应用,可加以研究并推广之。
Objective To analyze the clinical efficacy of targeted health education with interferon nebulized inhalation for infantile hand-foot-mouth disease. Methods 224 cases of children with HFMD were randomly divided into experimental group and control group of 112 cases. The experimental group was given targeted health education and basic treatment at the same time with recombinant human interferon α-2b inhalation; control group given targeted health education and basic treatment at the same time with ribavirin, Xiyanping treatment. Statistics two groups of patients with fever time, rash subsided time, hospitalization time, evaluation of two groups of treatment. Results The patients in experimental group had significantly shorter antipyretic time, rash subsidence time and hospitalization time than those in control group. The total effective rate was 91.96%, which was significantly higher than that of control group (61.61%, P <0.05). CONCLUSION: The related symptoms disappear rapidly in children with HFM combined with targeted health education and basic treatment of children with HFMD. The symptoms are obviously improved within a short period of time, which is worthy of clinical promotion and application and can be studied and popularized.