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目的观察门冬氨酸鸟氨酸治疗肝性脑病的临床疗效。方法随机选择肝性脑病患者62例,分为两组,治疗组31例(在常规综合治疗的基础上加用门冬氨酸鸟氨酸)和对照组31例(常规的综合治疗)治疗10d,观察治疗前后精神、行为、神志的变化情况。结果治疗组纠正精神紊乱、行为异常,改善神志的效果明显优于对照组,治疗组总有效率高于对照组(P<0.05)。结论门冬氨酸鸟氨酸治疗肝性脑病临床疗效明显,安全性好。
Objective To observe the clinical efficacy of ornithine aspartate in the treatment of hepatic encephalopathy. Methods Sixty-two patients with hepatic encephalopathy were randomly divided into two groups: 31 in the treatment group (with ornithine aspartate on the basis of conventional comprehensive treatment) and 31 in the control group (conventional combined treatment) for 10 days , Observe the changes of mental, behavioral and conscience before and after treatment. Results The treatment group corrected mental disorders, abnormal behavior, improvement of consciousness was significantly better than the control group, the total effective rate of the treatment group was higher than that of the control group (P <0.05). Conclusion Aspartic acid ornithine has obvious curative effect on hepatic encephalopathy and good safety.