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目的:探讨原发性甲状腺功能减退合并呼吸衰竭的临床特点和治疗方法。方法:回顾性分析2010-01-2014-06我院治疗的3例及2008-10-2009-02在宣武医院进修期间急诊治疗的2例原发性甲状腺功能减退合并呼吸衰竭的患者临床资料。结果:原发性甲状腺功能减退合并呼吸衰竭多见于既往未诊断甲状腺功能减退,未予治疗,病情严重时发生意识障碍、贫血、低钠血症,出现呼吸衰竭,需上呼吸机辅助呼吸治疗,原发性甲状腺功能减退表现常被掩盖,易漏诊。呼吸机治疗及甲状腺替代治疗后可改善低氧和高碳酸血症。结论:原发性甲状腺功能减退合并呼吸衰竭时机械通气是最有效手段之一,早期确诊及早期使用甲状腺激素替代治疗可以有效的治疗疾病,利于撤机。
Objective: To investigate the clinical features and treatment of primary hypothyroidism combined with respiratory failure. Methods: The clinical data of 3 patients who were treated in our hospital from January 2010 to June 2014 and 2 patients with primary hypothyroidism and respiratory failure who were treated by emergency at Xuanwu Hospital during the period of 2008-10-2009-02 were retrospectively analyzed. Results: Primary hypothyroidism combined with respiratory failure more common in the past not diagnosed with hypothyroidism, no treatment, when the condition is serious, disturbance of consciousness, anemia, hyponatremia, respiratory failure, requiring ventilator assisted breathing treatment, Primary hypothyroidism is often overshadowed performance, easy to miss. Ventilator therapy and thyroid replacement therapy improve hypoxemia and hypercapnia. Conclusions: Mechanical ventilation is one of the most effective measures for primary hypothyroidism combined with respiratory failure. Early diagnosis and early use of thyroid hormone replacement therapy can effectively treat the disease and facilitate weaning.