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肾上腺髓质增生(Adrenal Medullary Hyperplasia,AMH)是一种十分罕见的疾病,目前国内外文献报道仍不多。我院自1981年以来共收治2例,均经病理证实。现报告如下。 病例摘要 例1,女性,52岁。因发作性头痛、心悸4月,于1987年3月4日入院。检查期间症状反复发作,血压为20.8-26/13-16.9kPa,伴头痛、心悸、出汗。平时血压15.6/10.4kPa,体检无异常,拟诊“嗜铬细胞瘤”。酚妥拉明试验强阳性,注射酚妥拉明5mg后,血压降为零,经抢救后恢复正常。此后病人又连续几天反复出现低血压、休克、终因抢救无效死亡。实验室检查:空腹血糖2次分别为6.7与7.7mmol/L。发作时尿儿茶酚胺测定>180μg/24h。
Adrenal medulla hyperplasia (AMH) is a very rare disease and there are still few reports in the literature at home and abroad. In our hospital, 2 cases have been treated since 1981, all confirmed by pathology. The report is as follows. Case summary Example 1, female, 52 years old. He was admitted to hospital on March 4, 1987 because of episodic headache and palpitations in April. Repeated onset symptoms during the examination, blood pressure 20.8-26/13-16.9kPa, with headache, palpitations, sweating. Normal blood pressure 15.6/10.4kPa, no abnormal physical examination, the diagnosis of “pheochromocytoma.” The phentolamine test was strongly positive. After 5 mg of phentolamine was injected, blood pressure dropped to zero and returned to normal after rescue. Since then, the patient has repeatedly suffered from low blood pressure, shock, and ultimately died due to rescue. Laboratory tests: Fasting blood glucose was 6.7 and 7.7 mmol/L, respectively. Urine catecholamines were detected at the time of seizures >180μg/24h.