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肾素——血管紧张素——醛固酮(简称RAA)系统参与体内血压、细胞外液容量及肾功能的调节,临床上与肾脏疾病特别是肾性高血压关系十分密切。由于RAA 系统两种有效成分是血管紧张素Ⅱ(AT Ⅱ)和醛固酮,故本文观测了肾血管性高血压和肾实质性高血压患者血浆中ATⅡ—醛固酮水平,并与不伴有高血压的肾实质性疾病患者和健康人作了对照,初步探讨了其临床意义。
Renin-angiotensin-aldosterone (RAA) system is involved in the regulation of blood pressure, extracellular fluid volume and renal function in vivo, and is closely related to renal diseases, especially renal hypertension. Because the two active ingredients of RAA system are angiotensin Ⅱ (AT Ⅱ) and aldosterone, we observed the levels of plasma ATⅡ-aldosterone in patients with renovascular hypertension and renal parenchymal hypertension and compared with those without hypertension Patients with renal parenchymal disease and healthy people were compared, preliminary study of its clinical significance.