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心脏的形成需要多胚层来源的细胞间的相互作用,是各种细胞迁移、分化和十分精确组合的结果[1]。近年来的研究证明,这种细胞迁移、分化和组合受一系列基因调控。这些与心脏发育相关的基因都是长期种系发展中保存下来的。细胞迁移、分化和组合,基因异常可导致心血管畸形。从低
The formation of the heart requires cell-to-cell interactions of the embryonic germ layer and is the result of a combination of cell migration, differentiation, and very precise integration [1]. In recent years, studies have shown that this cell migration, differentiation and combination of a series of gene regulation. These genes associated with heart development are preserved in long-term germline development. Cell migration, differentiation and combination, genetic abnormalities can lead to cardiovascular malformations. From low