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目的:评估碱性成纤维细胞生长因子治疗视神经萎缩的疗效。方法:应用碱性成纤维细胞生长因子治疗视神经萎缩30例(39只眼),并与常规治疗(三磷酸腺苷、辅酶A)的病例进行对照观察,以视觉诱发电位作为治疗前后主要观察指标。结果:治疗组与对照组比较差异有显著性(P<0.01)。结论:碱性成纤维细胞生长因子是治疗视神经萎缩的更为有效的方法。
Objective: To evaluate the efficacy of basic fibroblast growth factor in the treatment of optic atrophy. Methods: 30 cases (39 eyes) of optic nerve atrophy were treated with basic fibroblast growth factor and compared with routine treatment (adenosine triphosphate and coenzyme A). The visual evoked potentials were taken as the main observation indexes before and after treatment. Results: The difference between the treatment group and the control group was significant (P <0.01). Conclusion: Basic fibroblast growth factor is a more effective method for the treatment of optic atrophy.