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肿瘤特异的免疫组化标记物对于鉴别恶性小圆细胞肿瘤有着重要的作用。锥-杆同源异型盒包含基因(the cone-rod homeobox-containing gene,CRX)是一种转录因子,可以选择性表达于视网膜感光细胞。有研究显示,CRX抗体是鉴别视网膜母细胞瘤与其他颅内恶性小圆细胞肿瘤的一种有价值的免疫组化标记物。但是,CRX免疫组化标记在中枢神经系统以外的转
Tumor-specific immunohistochemical markers for the identification of malignant small cell tumors have an important role. The cone-rod homeobox-containing gene (CRX) is a transcription factor that can be selectively expressed on retinal photoreceptors. Studies have shown that CRX antibody is a valuable immunohistochemical marker for differentiating retinoblastoma from other intracranial malignant orpithelial tumors. However, CRX immunohistochemistry marks a turn outside the central nervous system