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山西省稷山县痔瘘医院于1973年研制成一种局部长效止痛液,几年来他们用以解决肛门术后疼痛取得了显著效果。我们受山西省卫生厅委托配合作些动物实验,以探讨其止痛机理。我们用该药主要成分美蓝注射液超生体染色,用光镜与电镜观察小白鼠腹壁神经纤维及其周围的成纤维细胞的变化。初步实验观察如下: 材料与方法实验动物用体重32～42克的小白鼠12
Dingshan County Hospital in Shanxi Province was developed in 1973 as a local long-acting analgesic solution, and they have achieved significant results in resolving postoperative anal pain for several years. We were commissioned by the Health Department of Shanxi Province to collaborate with some animal experiments to explore its analgesic mechanism. We used the drug’s main component, methylene blue, for the ultrastructure staining. Light microscopy and electron microscopy were used to observe changes in the fibroblasts surrounding the abdominal wall nerve fibers of mice. The preliminary experimental observations were as follows: Materials and Methods Experimental animals, mice weighing 32 to 42 grams 12