论文部分内容阅读
目的调查我院药物不良反应发生的情况和特点。方法法收集我院2012~2015年314例药物不良反应报告,按患者的给药方式、相关药物品类、不良反应涉及器官及临床表现等方面进行汇总和分析。结果药物不良反应的发生与患者年龄、药物种类、用药方式及生产工艺有关。60岁以上老龄患者是药物不良反应的高发人群(50.32%);抗菌药物是引起药物不良反应的主要药物类型,其次为中药制剂;主要损害类型为皮肤及其附件损害(52.23%)。结论提高医务人员警惕性,加强监测抗菌类和中药注射剂药物不良反应,减少或避免药物不良反应,提高临床合理用药水平。
Objective To investigate the situation and characteristics of adverse drug reactions in our hospital. METHODS: A total of 314 reports of adverse drug reactions (MDRs) in our hospital from 2012 to 2015 were collected and analyzed according to the patient’s mode of administration, relevant drug categories, organ-related adverse reactions and clinical manifestations. Results The incidence of adverse drug reactions and patient age, type of drug, drug use and production processes. Elderly patients over the age of 60 were the most frequently reported adverse drug reactions (50.32%). Antibiotics were the major drug causing adverse drug reactions, followed by traditional Chinese medicine preparations. The main types of damage were skin and its accessories (52.23%). Conclusion To improve the vigilance of medical personnel, strengthen the monitoring of adverse reactions of antimicrobial drugs and traditional Chinese medicine injections, reduce or avoid adverse drug reactions, and improve the clinical rational use of drugs.