论文部分内容阅读
[目的]探讨放射性核素肾动态显像联合血清及CT检测中晚期宫颈癌肾功能评价的临床价值。[方法]回顾性分析2008年1月至2009年6月217例ⅡB～Ⅳ期宫颈癌初治患者放射性核素肾动态显像,CT和血清肌酐检查的结果,对其单独和联合检测肾功能异常进行诊断一致性分析。[结果]核素肾动态显像发现排泄异常和GFR异常分别为118例(54.38%)、141例(64.98%);CT发现肾脏及输尿管扩张31例(14.29%),血清肌酐发现异常13例(5.99%)。核素肾动态显像(GFR)、血肌酐、核素肾动态显像(GFR)+血肌酐、核素肾动态显像(排泄)+血肌酐、核素肾动态显像(GFR)+血清肌酐+CT、核素肾动态显像(排泄)+血肌酐+CT 6种检查与“标准”比较诊断肾功能异常有一致性,Kappa分别为0.187、0.175、0.175、0.124、0.099和0.064,P均<0.85。[结论]99mTc-DTPA肾动态显像+GFR测定方法简便,能早期观察肾脏损害程度,可作为一项评价宫颈癌早期肾损害有价值的指标。
[Objective] To investigate the clinical value of radionuclide renal dynamic imaging combined with serum and CT in detecting the renal function of advanced cervical cancer. [Methods] The results of radionuclide renal dynamic imaging, CT and serum creatinine examination in 217 newly diagnosed cervical cancer patients with stage ⅡB-Ⅳ cervical cancer from January 2008 to June 2009 were retrospectively analyzed. The renal function Abnormalities Diagnostic consistency analysis. [Results] Abnormalities of excretion and abnormal GFR were found in 118 cases (54.38%) and 141 cases (64.98%) in the radionuclide dynamic imaging. Thirteen cases (14.29%) of renal and ureter dilatation were found in CT and 13 cases were abnormal in serum creatinine (5.99%). (GFR), serum creatinine, GFR + serum creatinine, radionuclide renal dynamic imaging (excretion) + serum creatinine, GFR + serum Creatinine + CT, radionuclide renal dynamic imaging (excretion) + serum creatinine + CT were consistent with the “standard” comparison of renal dysfunction, Kappa were 0.187,0.175,0.175,0.124,0.099 and 0.064 , P <0.85 respectively. [Conclusion] 99mTc-DTPA renal dynamic imaging + GFR assay is simple and can be used to observe the degree of renal damage early, which can be used as a valuable index to evaluate the early renal damage of cervical cancer.