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目的探讨羟乙基纤维素(德纳泰)在肝脏切除术后的止血效果及其安全性。方法98例接受肝脏部分切除的患者随机分成两组。其中55例患者在术后肝脏断面应用羟乙基纤维素(德纳泰)止血，43例患者在术后肝断面应用氩气刀止血。观察两组患者术后引流量和引流液血红蛋白浓度差异性。结果德纳泰组患者术后第2d腹腔引流液血红蛋白浓度(18.15±5.13，1g/L)明显低于氩气刀组患者(39.01±4.03，3g/L)；德纳泰组患者术后腹腔引流液总量(232.03±82.69，3ml)明显少于氩气刀组(291.65±117.97，4ml)。而两组患者在术后并发症发生率上并无明显差别。结论在肝脏手术后，相比用氩气刀方法止血羟乙基纤维素(德纳泰)起效更快、止血效果更好。羟乙基纤维素(德纳泰)是一种安全、有效的止血材料，适合在外科手术中推广。“,”Objective A new hydroxyethyl cel ulose is expected to be ef icacious and safe as a haemostatic treatment in hepatic resection. Methods 98 patients requiring liver resection were divided into two groups randomly. Application of hydroxyethyl cel ulose (n=55) or argon beamer (argon beam coagulator) (n=43) as haemostatic treatment. Patients with coagulation disorders were excluded. The volume and haemoglobin cocentration of drainage fluid were measured. Results Haemoglobin concentration of drainage fluid was significantly lower on day 2 after surgery in hydroxyethyl cel ulose patients (18.15±5.131g/L) than in argon beamer patients (39.01±4.033g/L). Also, the total volume of drainage fluid in hydroxyethyl cel ulose patients was significant lower than in argon beamer patients (232.03±82.693ml vs 291.65±117.974ml). Conclusion Hydroxyethyl cel ulose is superior to argon beamer in obtaining ef ective and fast intraoperative haemostasis. The safety data show hydroxyethyl cel ulose to be tolerable and safe for haemostatic treatment in liver resection.