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目的探讨米索前列醇配伍利多卡因在早孕未产妇行人工流产术时的镇痛效果。方法孕6～10周自愿要求终止妊娠的未产妇200例随机等分为两组,实验组于人工流产术前1h阴道后穹窿放置米索前列醇200μg,术中宫颈旁4点、10点注射2%利多卡因共5ml,对照组不使用任何药物,比较两组患者在扩宫效果、镇痛效果、人工流产综合征发生率方面的差异。结果两组患者扩宫效果、镇痛效果、人工流产综合征发生率方面差异有统计学意义(P<0.05)。结论米索前列醇配伍利多卡因用于人工流产术具有显著扩张宫颈和较好镇痛效果,是一种有效、安全、简便、经济的方法。
Objective To investigate the analgesic effect of misoprostol combined with lidocaine on abortion during first trimester of abortion. Methods Two hundred and ten pregnant women who volunteered for termination of pregnancy at 6-10 weeks of gestation were randomly divided into two groups. The experimental group was given misoprostol 200 μg at 1 h before induced abortion, 4 at the cervix and 10 injections 2% lidocaine 5ml, the control group did not use any drugs, comparing the two groups of patients in the expansion effect, analgesic effect, the incidence of abortion syndrome differences. Results There were significant differences in the effect of expanding the palace, analgesic effect and abortion syndrome between the two groups (P <0.05). Conclusion Misoprostol combined with lidocaine for abortion has a significant expansion of the cervix and better analgesic effect, is an effective, safe, simple and economical method.