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本文测定了３１例急性心肌梗塞（ＡＭＩ）患者血浆甘丙素（ＧＡＬ）的放免活性，结果显示ＡＭＩ患者急性期各次血浆ＧＡＬ水平明显高于对照组，伴高血压、糖尿病和心功能不全者升高更显著，ＧＡＬ与内皮素（ＥＴ）、血糖水平均呈正相关。实验性心肌梗塞大鼠血浆ＧＡＬ、血清肌酸激酶（ＣＫ）、ＣＫ同功酶（ＣＫ－ＭＢ）、丙二醛（ＭＤＡ）含量亦明显高于对照大鼠。用ＧＡＬ抗血清治疗心肌梗塞大鼠，减少坏死面积４５．４％和缩小了梗塞范围４７．１％，亦明显降低了血浆ＧＡＬ水平，抑制血清ＣＫ、ＣＫ－ＭＢ、ＭＤＡ活性，提示早期阻断ＧＡＬ的生物学效应，对防治ＡＭＩ有重要意义。
In this study, 31 patients with acute myocardial infarction (AMI) in patients with plasma galactosamine (GAL) radioactivity showed that AMI in patients with acute plasma GAL levels were significantly higher than the control group, with hypertension, diabetes and cardiac insufficiency were elevated More significant, GAL and endothelin (ET), blood glucose levels were positively correlated. Plasma GAL, creatine kinase (CK), CK isoenzyme (CK-MB) and malondialdehyde (MDA) in experimental myocardial infarction rats were also significantly higher than those in control rats. Treatment of myocardial infarction rats with GAL antiserum reduced the area of necrosis by 45.4% and the infarction area by 47.1%, also significantly reduced the level of plasma GAL, inhibited the activity of serum CK, CK-MB and MDA, suggesting early blockade The biological effects of GAL are of great significance for the prevention and treatment of AMI.