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皮肤T细胞淋巴瘤(CTCL)是原发于皮肤,以皮肤损害为主要表现,组织病理及免疫组化见大量异形T淋巴细胞浸润的淋巴瘤,临床见蕈样肉芽肿(MF)、Sezary综合征(SS)和Paget样网织细胞增生症(PR),其肿瘤浸润细胞以T辅助细胞(T_H)亚群为主,具有向表皮性特征。本实验应用免疫组化ABC技术及有关McAb,对14例蕈样肉芽肿患者皮损中T淋巴细胞及亚群分布进行观察。
Cutaneous T-cell lymphoma (CTCL) is a primary form of lymphoma that is primary to the skin and is characterized by skin lesions. Histopathologic and immunohistochemical findings include numerous forms of T-cell infiltration of lymphoma, and clinical findings include mycosis fungoides (MF), Sezary’s syndrome Signs (SS) and Paget-like reticulocyte proliferation (PR), the tumor infiltrating cells to T helper cells (T_H) subpopulations, with epidermal characteristics. In this study, the use of immunohistochemical ABC technology and McAb, 14 patients with mycosis fungoides in patients with lesions in T lymphocytes and subpopulations were observed.