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本文报告邻苯二甲酸二辛酯(DOP)对雄性大鼠的生殖毒性。Wistar雄性大鼠灌胃DOP200、1000、5000mg/kg,另设对照组。每天染毒一次,持续4周。结果表明,染毒期间,染毒组与对照组比较,睾丸重量、附睾重量明显降低。睾丸模经、竖径明显缩小。精子数量、活力显著减少或降低;精子畸形率则明显升高。血清睾酮和睾丸组织中睾
This article reports the reproductive toxicity of dioctyl phthalate (DOP) in male rats. Wistar male rats intragastric DOP200,1000,5000mg / kg, another set of control group. Apply once daily for 4 weeks. The results showed that during the exposure period, the weight of testis and the weight of epididymis significantly decreased in the exposed group compared with the control group. Testicular die, vertical diameter was significantly reduced. Sperm count, vitality significantly reduced or reduced; sperm deformity rate was significantly increased. Serum testosterone and testis in testis