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我院自1965年至1986年底共施行各种类型角膜移植手术3482眼,其中角膜移植术后早期发生植片感染5眼,眼内炎2眼。植片感染发生率为0.14%,眼内炎发生率为0.05%。这7个眼睛经再次或第三次角膜移植手术,配合局部和全身使用抗菌素治疗,追踪36天至7年,保存眼球6眼,因感染未能控制而做眼内容挖除一眼。在保存眼球的6眼中,植片保持透明5眼,半透明一眼。视力达到0.3者2眼,0.2者1眼,眼前指数至0.1者3眼。本文还对角膜移植术后早期感染发生的潜在危险因素,感染的致病菌,感染类型与手术方式的关系作了讨论,并就治疗角膜移植术后早期感染的方法作了探讨。
In our hospital from 1965 to the end of 1986, a total of 3482 corneal allograft operations were performed, of which 5 were infected with early phytoplasty and 2 were endophthalmitis. The incidence of graft infection was 0.14%, the incidence of endophthalmitis was 0.05%. The seven eyes were treated with a second or third corneal transplant, followed by topical and systemic antibiotic treatment, followed for 36 days to 7 years, preserved for 6 eyes, and removed due to uncontrolled infection. Of the 6 eyes that held the eyeball, 5 were transparent and one was translucent. Visual acuity reached 0.3 in 2 eyes, 0.2 in 1 eye, anterior index to 0.1 in 3 eyes. This article also discusses the potential risk factors of early infection after corneal transplantation, the pathogens of infection, the relationship between the type of infection and the surgical approach, and discusses the treatment of early infection after corneal transplantation.