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目的:观察莫西沙星治疗急性盆腔炎的临床疗效和安全性。方法:观察病例70例,随机分为试验组38例,对照组32例,试验组静脉滴注莫西沙星注射剂400 mg,1次/d;对照组静脉滴注左氧氟沙星注射剂400 mg,1次/d,疗程均为7~14 d。结果:试验组和对照组的临床有效率分别为97%和84%,细菌清除率分别为82%和69%,两组临床有效率及细菌清除率比较差异均有统计学意义(P<0.05);试验组和对照组不良反应发生率比较差异无统计学意义(P>0.05)。结论:莫西沙星注射剂治疗急性盆腔炎疗效确切,安全性好,有较高的临床应用价值。
Objective: To observe the clinical efficacy and safety of moxifloxacin in the treatment of acute pelvic inflammatory disease. Methods: A total of 70 cases were observed and randomly divided into experimental group (38 cases) and control group (32 cases). Moxifloxacin 400 mg once a day was used as the experimental group. The control group was given 400 mg levofloxacin once a day, d, treatment are 7 ~ 14 d. Results: The clinical efficacies were 97% and 84% in the test group and the control group respectively, and the bacterial clearance rate was 82% and 69% respectively. There was significant difference between the two groups in clinical efficacy and bacterial clearance (P <0.05 ). There was no significant difference in the incidence of adverse reactions between the experimental group and the control group (P> 0.05). Conclusion: Moxifloxacin injection for the treatment of acute pelvic inflammatory disease is effective, safe and has high clinical value.