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目的探讨呼吸兴奋剂加营养支持治疗肺性脑病的临床疗效。方法将我院收治的104例肺性脑病患者,随机分为观察组和对照组,每组各52例。对照组给予抗感染、吸氧及畅通呼吸道等常规综合治疗与呼吸兴奋剂治疗,观察组在此基础上加营养支持治疗,疗程均为7d。结果治疗前两组PaO2、PaCO2比较差异无统计学意义(P>0.05);治疗后两组PaO2均显著上升、PaCO2显著下降,差异有统计学意义(P<0.05);两组之间比较,治疗后观察组PaO2、PaCO2的改善优于对照组,差异有统计学意义(P<0.05)。观察组总有效率94.23%,显著高于对照组80.77%,差异有统计学意义(P<0.05)。结论呼吸兴奋剂加营养支持治疗肺性脑病安全有效,值得临床推广。
Objective To investigate the clinical effect of respiratory stimulant plus nutritional support on pulmonary encephalopathy. Methods 104 cases of pulmonary encephalopathy admitted to our hospital were randomly divided into observation group and control group, with 52 cases in each group. The control group was given anti-infective, oxygen and smooth breathing and other conventional comprehensive treatment and respiratory stimulant treatment, the observation group on this basis plus nutritional support treatment, treatment were 7d. Results There was no significant difference in PaCO 2 and PaCO 2 between the two groups before treatment (P> 0.05). After treatment, both PaO 2 increased significantly and PaCO 2 decreased significantly (P <0.05) The improvement of PaO2 and PaCO2 in the observation group after treatment was better than that in the control group, with significant difference (P <0.05). The total effective rate was 94.23% in the observation group, which was significantly higher than that in the control group (80.77%), the difference was statistically significant (P <0.05). Conclusion Respiratory stimulants plus nutritional support for the treatment of pulmonary encephalopathy safe and effective, worthy of clinical promotion.