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目的:探讨孕期妇女的红细胞免疫功能,并研究血红蛋白含量对红细胞免疫功能的影响。方法:对38例孕期妇女进行红细胞C3b补体受体花环(RBC-C3bRR)、红细胞免疫复合物受体花环(RBC-ICR)、红细胞辅助因子(RIER)、红细胞抑制因子(RIFR)采用酵母多糖花环试验,血红蛋白含量采用自动血球计数仪测定法。结果:发现孕妇(RBC-C3bRR)、红细胞辅助因子(RIER)明显降低,而RBCICR、红细胞抑制因子(RIFR)明显升高,并发现RBC-C3bRR、RIER与血红蛋白浓度呈正相关,RBC-ICR、RIFR与血红蛋白浓度呈负相关。结论:孕期妇女贫血可导致继发性红细胞免疫功能低下。
Objective: To investigate the erythrocyte immune function in pregnant women and to study the influence of hemoglobin content on immune function of erythrocytes. Methods: RBC-C3bRR, RBC-ICR, RIER and RIFR in 38 pregnant women were detected by using Zymosan Test, hemoglobin content using automatic blood cell counting method. Results: RBC-C3bRR and RIER were significantly decreased, but RBCICR and erythrocyte inhibitory factor (RIFR) were significantly increased. RBC-C3bRR and RIER were positively correlated with hemoglobin concentration. RBC-ICR, RIFR And hemoglobin concentration was negatively correlated. Conclusion: Anemia in pregnant women can cause secondary erythrocyte immune dysfunction.