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胃十二指肠出血常见于慢性消化性溃疡,应激性溃疡及急性胃粘膜病变等。近年来内科主要采用内窥镜及H_2受体拮抗剂进行止血治疗。H_2受体拮抗剂止血机理主要是抑制胃酸分泌。所以该药对应激性溃疡及急性胃粘膜病变的止血作用是有限的。作者对8例使用H_2受体拮抗剂治疗无效的胃十二指肠大出血患者,采用了胰泌素持续静脉滴注治疗,收到良好效果。8例患者均为男性,年龄24～68岁,平均48.9岁。应激性溃疡4例,急性胃粘膜病变3例,慢性消化性溃疡1例。出血部位是胃出血6例,十二指肠出血2例。4例应激性溃疡患者出血量中等,其它
Gastroduodenal bleeding common in chronic peptic ulcer, stress ulcer and acute gastric mucosal lesions. In recent years, endoscopists mainly use endoscopy and H 2 receptor antagonist to stop bleeding. H 2 receptor antagonist hemostasis mechanism is mainly to inhibit gastric acid secretion. Therefore, the drug has a limited hemostatic effect on stress ulcer and acute gastric mucosal lesions. The authors of 8 patients with H 2 receptor antagonist treatment ineffective gastroduodenal bleeding in patients with sustained secretion of secretin therapy, received good results. All 8 patients were male, aged from 24 to 68 years, with an average of 48.9 years. 4 cases of stress ulcer, 3 cases of acute gastric mucosal lesions and 1 case of chronic peptic ulcer. Bleeding site is bleeding in 6 cases, 2 cases of duodenal hemorrhage. 4 cases of stress ulcer patients with moderate bleeding, others