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目的分析糖尿病心肌病的危险因素。方法将90例糖尿病患者分为糖尿病心肌病组44例和单纯糖尿病组46例,分别测定脑钠肽(BNP)、超敏C-反应蛋白(hs-CRP)、胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-L)、低密度脂蛋白胆固醇(LDL-L)、糖化血红蛋白(Hb A1c)、空腹血糖(FPG),记录糖尿病病程。比较2组上述指标,分析糖尿病心肌病的危险因素。结果糖尿病心肌病组LDL-L、TC水平较单纯糖尿病组升高(P<0.05);Hb A1c、FPG、BNP、hs-CRP水平及病程较单纯糖尿病组明显升高(P<0.01)。结论糖尿病心肌病与脑钠肽水平密切相关,糖尿病病程及hs-CRP是糖尿病心肌病的危险因素。
Objective To analyze the risk factors of diabetic cardiomyopathy. Methods Ninety diabetic patients were divided into diabetic cardiomyopathy group (n = 44) and diabetes mellitus group (n = 46). The levels of BNP, hs-CRP, TC, triglyceride TG, HDL-L, LDL-L, Hb A1c, and fasting plasma glucose (FPG) were recorded. The course of diabetes was recorded. The above two indexes were compared to analyze the risk factors of diabetic cardiomyopathy. Results The levels of LDL-L and TC in diabetic cardiomyopathy group were significantly higher than those in simple diabetic group (P <0.05). The levels of Hb A1c, FPG, BNP, hs-CRP and their duration were significantly higher than those in simple diabetic group (P <0.01). Conclusions Diabetic cardiomyopathy is closely related to the level of brain natriuretic peptide. Diabetes duration and hs-CRP are the risk factors of diabetic cardiomyopathy.