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本文测定了78例高危妊娠和36例正常孕妇(均为单胎初产)血清游离雌三醇(FE_3)和胎盘泌乳素(HPL),重点比较了FE_3和HPL 诊断妊高征时胎儿合并症的敏感性、特异性和预测价值。材料与方法高危妊娠组(妊高征59例,胎儿宫内生长迟缓9例,过期妊娠10例)。年龄22~35岁,孕龄31~43周;对照组年龄21~35岁,孕龄31~42周。妊高征按1987年全国妊高征会议标准分为轻中重三组,另分出蛋白尿组(尿蛋白≥+)和子痫组(发作抽搐);过期妊娠指孕龄≥42周,伴下列情况之一者;尿E/C比值<15,胎动减少、B 超或羊膜镜发现羊水少而混浊;IUGR 指胎儿出生体重低于正常值—2SD 者(本文为2684.4g),胎儿合并症指IUGR 或/和胎儿宫内窘迫(简称胎窘,以妊高征伴羊水混浊Ⅱ°以上为标准)。血清制备后,置-20℃贮存待测。HPL 测定采
This article measured serum free estriol (FE_3) and placental prolactin (HPL) in 78 high-risk pregnancies and 36 normal pregnant women (all singleton primiparous), with a focus on the comparison of FE_3 and HPL in the diagnosis of fetal complications during pregnancy-induced hypertension Sensitivity, specificity and predictive value. Materials and Methods High-risk pregnancy group (PIH 59 cases, intrauterine growth retardation in 9 cases, 10 cases of expired pregnancy). Age 22 to 35 years old, gestational age 31 to 43 weeks; control group aged 21 to 35 years old, gestational age 31 to 42 weeks. PIH according to the 1987 National Conference on pregnancy induced hypertension standard is divided into three groups of light and heavy, and the other divided into proteinuria (urinary protein ≥ +) and eclampsia group (seizure); overdue pregnancy refers to gestational age ≥ 42 weeks, with One of the following conditions; urinary E / C ratio <15, fetal movement decreased, B or amniotic fluid found amniotic fluid less turbid; IUGR refers to the fetus birth weight less than the normal -2SD (2684.4g in this article), fetal complications Refers to IUGR or / and fetal distress (referred to as fetal embolism, PIH with amniotic fluid turbidity Ⅱ ° above). Serum preparation, set -20 ℃ storage to be tested. HPL mining mining