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目的观察慢性乙型肝炎患者的中医证候类型分布规律,对不同证候类型患者生命质量进行评价。方法:采用慢性乙肝中医证候采集量表和SF-36量表,对692例慢性乙肝患者进行中医证候类型分布情况和生命质量的测量与评价结果位居前五位的证候类型分别为脾胃湿热、肝胆湿热、肝脾湿热、肝郁脾虚、肝郁气滞。不同证候类型在SF-36中关于生理健康的4个维度中均存在显著差异(P<0.01);在关于心理健康的4个维度中,仅在“情绪角色功能”存在差异(P<0.05)。在SF-36各个维度的评分中,年龄、性别与证候类型间存在交互作用。结论692例慢性乙肝患者排在第一位的证候类型是脾胃湿热,为临床从脾论治慢性乙肝提供了依据,突破了既往从肝论治的局限。中医辨证分型是对不同生理状况患者的有效区分。
Objective To observe the distribution of TCM syndromes in patients with chronic hepatitis B and evaluate the quality of life of patients with different syndrome types. Methods: Chronic Hepatitis B TCM Syndrome Collection Scale and SF-36 Scale were used to investigate the distribution of TCM syndrome types and quality of life measurement and evaluation of 692 cases of chronic hepatitis B patients in the top five syndrome types Spleen and stomach heat, liver and gallbladder heat, liver and spleen dampness, liver depression spleen, liver qi stagnation. There were significant differences among different dimensions of SF-36 in four dimensions of physiological health (P <0.01). Among the four dimensions of mental health, there were only differences in “emotional function” (P <0.05). Among the scores of SF-36 in all dimensions, there is an interaction between age, gender and syndrome type. Conclusions 692 cases of chronic hepatitis B patients in the first syndrome type is the spleen and stomach dampness, for the clinical treatment of chronic hepatitis B from the spleen provides a basis, breaking the past from the limitations of liver treatment. TCM syndrome differentiation is the effective differentiation of patients with different physiological conditions.