高剂量率后装腔内放射并手术治疗宫颈癌

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自1992年2月至1994年10月,我们对32例Ⅱ期以内、局部瘤体较大、年纪较轻的宫颈癌病人,在行体外及高剂量率后装内放疗后3周左右,再行全子宫或次广泛子宫切除术。全组病例手术经过顺利,未发现任何并发症。本组32例病人的切除标本全部送病检,作多点切片,观察有无癌组织存在并描述对射线反应的程度。32例中,放疗反应I级者3例,Ⅱ级者13例,Ⅲ级者历例。按病理类型分析,23例鳞癌中Ⅱ级反应8例、Ⅲ级反应15例(65.2%)。8例腺癌中I级反应2例,Ⅱ级反应5例,Ⅲ级反应者仅1例。1例鳞腺癌为I级反应。术后随访2~30个月未发现特殊并发症,30例病人无癌生存,1例局部复发,1例左锁骨上转移。 From February 1992 to October 1994, we treated 32 patients with stage Ⅱ, local tumor larger, younger cervical cancer patients undergoing external and high dose rate after the installation of radiotherapy within about 3 weeks, and then Line hysterectomy or subtotal hysterectomy. All patients underwent a successful operation without any complication. The group of 32 patients with all resected specimens sent to the hospital for multi-slice, observe the presence of cancer and describe the degree of response to radiation. In 32 cases, there were 3 cases with grade I radiotherapy, 13 cases with grade Ⅱ, and Ⅲ cases with history. According to the pathological type, there were 8 cases of grade Ⅱ reaction in 23 cases of squamous cell carcinoma and 15 cases of grade Ⅲ reaction (65.2%). There were 2 cases of grade I reaction, 5 cases of grade Ⅱ reaction and 1 case of grade Ⅲ reaction in 8 cases of adenocarcinoma. One case of squamous carcinoma was grade I response. No special complication was found after 2 to 30 months of follow-up. There was no cancer in 30 patients, 1 case of local recurrence and 1 case of left supraclavicular metastasis.
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