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目的 探讨逼尿肌等容收缩试验 (DIT)的临床价值。方法 对排尿异常病人 89例 ,其中前列腺增生 (BPH)5 9例 ,进行全面的尿动力学检查 (包括DIT)。结果 (1)最大逼尿肌等容收缩压 (Piso)与逼尿肌收缩速度呈正相关(r =0 .847,P <0 .0 0 1) ;(2 )Piso随膀胱容量增加而显著下降 (P <0 .0 0 1) ;(3)CT80与VE呈负相关 (r =- 0 .5 2 0 ,P <0 .0 1) ;(4 )DIT参数与膀胱排空至容量为 40ml时膀胱壁收缩之速度 (dL/dT 40 )无明显相关性 ;(5 )Piso与BPH梗阻程度呈正相关性 (r =0 .6 78,P <0 .0 0 1) ;(6 )当残余尿量≥ 10 0ml,逼尿肌储能 (DR)显著下降 (P <0 .0 0 1) ;(7)不稳定膀胱组Piso显著高于稳定膀胱组 (P <0 .0 1)。结论 DIT是一项简单适用的 ,用来测定逼尿肌收缩力的尿动力学检查 ,应用于BPH病人很有临床价值。
Objective To investigate the clinical value of detrusor isovolumetric contraction test (DIT). Methods 89 patients with dysuria, including benign prostatic hyperplasia (BPH) 59 cases, a comprehensive urodynamic examination (including DIT). Results (1) The maximum detrusor isovolumic systolic pressure (Piso) was positively correlated with detrusor contractility (r = 0.847, P <0.01). (2) Piso decreased significantly with the increase of bladder capacity (P <0.01); (3) CT80 was negatively correlated with VE (r = - 0.520, P <0.01); (4) DIT parameters and bladder emptying to a volume of 40ml (5) There was a positive correlation between Piso and BPH obstruction (r = 0.788, P <0.01); (6) When residual Urine volume ≥10 0ml, detrusor energy storage (DR) decreased significantly (P <0.01); (7) Piso in unstable bladder group was significantly higher than that in stable bladder group (P <0.01). Conclusion DIT is a simple and applicable urodynamic study to determine the contractility of detrusor muscle and is of great clinical value in patients with BPH.