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目的:对ADC值诊断结节状及弥漫生长外周带前列腺癌的价值进行初步评价。方法:对病理证实的35例外周带前列腺癌及22例外周带非肿瘤性病变的最小ADC值进行回顾性分析。结果:诊断结节状外周带前列腺癌,两位评估者所获的ROC曲线下面积(AUCs)分别为0.713(95%CI:0.566~0.866)及0.748(95%CI:0.605~0.890),诊断弥漫生长的外周带前列癌,评估者1及2的AUCs分别为0.943(95%CI:0.854,1.033)及0.876(95%CI:0.729,1.023),当ADC截断值设为1.02×10-3 mm2/s时,两种形状外周带前列腺癌的诊断的正确率分别为67.4%~70.5%及84.0%~85.7%。结论:ADC值对于外周带弥漫生长前列腺癌的诊断价值较高,对于外周带结节状前列腺癌的诊断价值中等。
Objective: To evaluate the diagnostic value of ADC in nodular and perinatal prostate cancer with diffuse growth. Methods: The minimal ADC values of 35 cases of peripheral prostate cancer and 22 cases of peripheral non-neoplastic lesions confirmed by pathology were analyzed retrospectively. Results: The area under the ROC curve (AUCs) was 0.713 (95% CI: 0.566-0.866) and 0.748 (95% CI: 0.605-0.890) for diagnosis of peripheral nodular prostate cancer. The diagnostic value AUCs were 0.943 (95% CI: 0.854, 1.033) and 0.876 (95% CI: 0.729, 1.023) for diffusely growing peripheral bands with evaluators 1 and 2, respectively. When ADC cutoff was set at 1.02 x 10-3 mm2 / s, the correct rate of diagnosis of prostate cancer with two kinds of peripheral bands was 67.4% -70.5% and 84.0% -85.7%, respectively. CONCLUSION: The ADC value is of high diagnostic value for the peripheral growth of diffusely growing prostate cancer and for the diagnosis of peripheral nodular prostate cancer.