Role of ADAM 10 and ADAM 17 in CD 16b Shedding Mediated by Different Stimulators

• 作 者: Sha Guo Min Peng Qing Zhao Wei
• 机 构: DepartmentofImmunology
• 出 处: 中国医学科学杂志：英文版
• 发表日期: 2012年2期
• 关键词: ADAM 短发夹RNA HEK293 金属蛋白酶 介导 光盘 稳定表达 免疫检测 a disintegrin and metalloproteinase 10
• 基金项目: Supported by the National Natural Science Foundatiop of China （30872287）.

Objective To investigate the main proteinases responsible for CD16b shedding under different stimulators. Methods HEK293 cell line stably expressing CD16b was constructed by lentivirus system. The cell line was then overexpressed with a disintegrin and me