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目的研究分析氟哌噻吨美利曲辛治疗难治性支气管哮喘合并负性情绪患者的临床效果。方法选取2013年5月至2015年5月郑州人民医院收治的难治性支气管哮喘合并负性情绪患者94例,随机分为两组,各47例。对照组采用常规治疗,观察组采用氟哌噻吨美利曲辛治疗,对比两组治疗前后HAMA、HAMD、ACT评分以及肺功能变化情况。结果观察组治疗后HAMA和HAMD评分均显著低于对照组,差异显著(P<0.05);观察组治疗后ACT评分明显高于对照组,差异显著(P<0.05);观察组治疗后FEV1%Pre、PEF指标显著高于对照组,差异显著(P<0.05)。结论氟哌噻吨美利曲辛治疗难治性支气管哮喘合并负性情绪患者效果显著,能够有效缓解患者负面情绪,改善肺功能,减轻哮喘症状,值得推广。
Objective To study the clinical efficacy of flupentixol and melitracen in refractory bronchial asthma patients with negative emotions. Methods From May 2013 to May 2015, 94 patients with refractory bronchial asthma with negative emotions admitted to Zhengzhou People’s Hospital were randomly divided into two groups (n = 47 in each group). The control group was treated with routine therapy. The observation group was treated with flupentixol and melitracen. The changes of HAMA, HAMD, ACT score and pulmonary function before and after treatment were compared between two groups. Results After treatment, the scores of HAMA and HAMD in the observation group were significantly lower than those in the control group (P <0.05). The ACT score of the observation group was significantly higher than that of the control group (P <0.05) Pre, PEF index was significantly higher than the control group, the difference was significant (P <0.05). Conclusion Flupentixol and melitracen are effective in patients with refractory bronchial asthma combined with negative emotions, which can effectively relieve the negative emotions of patients, improve lung function and relieve the symptoms of asthma, which deserves promotion.