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目的:研究大戟科植物猫眼草的化学成分。方法:运用硅胶、Sephadex LH-20、MCI等色谱进行分离纯化,通过红外光谱、紫外光谱、质谱、核磁共振等现代波谱学方法进行结构鉴定。结果:从猫眼草乙酸乙酯和正丁醇部位中分离得到了12个化合物,分别鉴定为:3β-羟基-7β-甲氧基-5-豆甾烯(1)、3β,22β-二羟基-7β-甲氧基-5-豆甾烯(2)、灰绿曲霉酰胺(3)、2,5-二羟基-4-甲氧基菲(4)、对羟基苯甲酸(5)、3-甲氧基-4-羟基苯甲酸(6)、灯盏花苷C(7)、5,7,4’-三羟基双氢黄酮(8)、山柰酚(9)、槲皮素(10)、科罗索酸(11)、金合欢素(12)。结论:除化合物9、10外,其余化合物均为首次从该植物中分离得到。
Objective: To study the chemical composition of Euphorbiaceae cat’s eye grass. Methods: Silica gel, Sephadex LH-20, MCI and other chromatographic separation and purification, by infrared spectroscopy, UV spectroscopy, mass spectrometry, nuclear magnetic resonance and other modern spectroscopic methods for structural identification. Results: Twelve compounds were isolated from the fractions of ethyl acetate and n-butanol in cat’s eye grass and identified as 3β-hydroxy-7β-methoxy-5-stigmatene (1), 3β, 22β-dihydroxy- (4), p-hydroxybenzoic acid (5), 3- (4-hydroxymethyl) (6), erigeron C (7), 5,7,4’-trihydroxyflavanone (8), kaempferol (9), quercetin (10) , Corosolic acid (11), acacetin (12). Conclusion: The compounds were isolated from this plant for the first time except compound 9,10.