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目的探讨老年2型糖尿病合并慢性阻塞性肺疾病(COPD)患者胰岛素抵抗和胰岛素功能情况。方法选取2011年3月至2013年3月我院门诊收治的2型糖尿病合并COPD患者50例为观察组,同期选取体检正常者44例为对照组,对两组研究对象的空腹胰岛素、空腹C肽、餐后胰岛素及糖负荷2 h C肽等指标进行检测比较。结果两组患者统计结果显示,观察组患者在胰岛素抵抗上较对照组明显上升,胰岛B细胞功能明显降低,空腹胰岛素、空腹C肽等观察指标与对照组比较,差异均有统计学意义(均P<0.05)。结论老年2型糖尿病合并COPD患者临床表现为胰岛素抵抗,胰岛β细胞功能下降,对此需要在临床治疗中给予积极的治疗和控制。
Objective To investigate the insulin resistance and insulin function in elderly patients with type 2 diabetes mellitus and chronic obstructive pulmonary disease (COPD). Methods From March 2011 to March 2013, 50 outpatients with type 2 diabetes mellitus and COPD admitted to our hospital were selected as the observation group. Forty-four healthy subjects were selected as the control group during the same period. The fasting insulin, fasting C Peptide, postprandial insulin and sugar load 2 h C peptide and other indicators were detected and compared. Results The statistic results of two groups showed that the patients in the observation group showed a significant increase in insulin resistance compared with the control group and the function of islet B cells was significantly decreased. The observation indicators such as fasting insulin and fasting C-peptide were significantly different from those in the control group P <0.05). Conclusion The clinical manifestations of senile type 2 diabetes mellitus combined with COPD are insulin resistance and the function of pancreatic β cells is decreased. Therefore, it is necessary to give active treatment and control in clinical treatment.