论文部分内容阅读
糖尿病(diabetes mellitus,DM)是以高血糖为主要表现的代谢紊乱,是由胰岛素分泌不足和/或胰岛素在靶组织作用缺陷所致,这两种缺陷可在诊断时共同存在,或在糖尿病表现出现以前就单独存在。随着时间推移,糖尿病病人有不同程度的胰岛细胞功能障碍和胰岛素抵抗。胰岛β细胞的胰岛素分泌不足是由于免疫介导的细胞破坏(1型糖尿病)或不能代偿胰岛素的需求增加(2型糖尿病)。研究表明,从胰岛细胞增
Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia and is caused by insufficient insulin secretion and / or insulin deficiency in the target tissue. Both of these defects may co-exist at diagnosis or may be manifested in diabetes mellitus Appeared before there alone. Over time, diabetic patients have varying degrees of islet cell dysfunction and insulin resistance. Inadequate insulin secretion from pancreatic β-cells is due to an increase in immune-mediated cell destruction (type 1 diabetes) or a failure to compensate for insulin (type 2 diabetes). Studies have shown that from islet cells increased