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目的:通过分析我院2011年4月到2012年9月门诊病人不合理应用抗生素的情况,为促进临床合理用提供依据,并且提出相应的解决措施。方法:本文采用回顾性调查,参考相关的法律法规、文献资料、临床用药资料以及药品的使用说明书,对我院门诊病人不合理使用抗生素进行统计学分析。结果:在本年度门诊病例中随机抽取15000份,其中使用了抗生素的病例有3050份,使用率为20.33%。这些病例中三联用药率为0.02%,双药联用率为2.51%,单独用药率为18.99%。通过分析发现不合理使用抗生素主要涉及到一下几个方面:剂量偏大、溶媒不当、疗程过长、重复用药、药物拮抗、毒性相加和用药指征不明确等。结论:通过统计学分析,可以发现临床不合理用药情况,从而促进、指导临床合理用药。
OBJECTIVE: To analyze the unreasonable use of antibiotics by outpatients in our hospital from April 2011 to September 2012, provide the basis for the promotion of clinical rational use, and propose corresponding solutions. Methods: In this paper, a retrospective survey, with reference to relevant laws and regulations, literature, clinical medication information and instructions for the use of drugs, hospital outpatient irrational use of antibiotics for statistical analysis. Results: 15000 outpatients were randomly selected from this year’s outpatient setting. Among them, 3050 cases were used antibiotics and the utilization rate was 20.33%. In these cases, triple drug use rate was 0.02%, dual drug combination rate was 2.51%, the single drug rate was 18.99%. Through the analysis found that unreasonable use of antibiotics mainly involves the following aspects: the dose is too large, improper solvent, the course is too long, repeated medication, drug antagonism, toxicity and medication indications are not clear. Conclusion: Through statistical analysis, we can find out the situation of irrational use of medicine in clinic so as to promote and guide clinical rational drug use.