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甲状腺素替代疗法对骨矿物质密度效应的研究结果仍有争议,该治疗使骨矿物质水平降低的报道促使提出应降低甲状腺素剂量的建议。研究人员在一大同种组病人中检测了长期应用甲状腺治疗对骨矿物质密度的效应。全部病人均因分化的甲状腺癌而施行甲状腺切除术,但病人没有其他的甲状腺疾病史。
The results of the study on the effect of thyroid hormone replacement therapy on bone mineral density are still controversial. The report of a decrease in the level of bone mineral caused by this treatment led to the suggestion of lowering thyroxine dosage. Researchers tested the effect of long-term thyroid treatment on bone mineral density in a large homogeneous group of patients. All patients underwent thyroidectomy for differentiated thyroid cancer, but the patient had no other history of thyroid disease.