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作者报告1979～1982年间北爱尔兰23例散发的Reye’s综合征,其诊断标准为:(1)有上呼吸道或胃肠道症状,伴有发热或水痘;(2)以血氨和/或血清转氨酶3倍升高,凝血酶原时间明显延长(与正常对照比较<40%)为特征的肝功能衰竭;(3)突然发生中枢神经系统紊乱,表现意识改变(伴有其他异常);(4)排除有类似临床特征的其他疾病。按Lovejoy分级方案对患儿的意识状态进行分级。17
The authors report 23 Reident’s syndromes distributed in Northern Ireland from 1979 to 1982 with diagnostic criteria of (1) upper respiratory or gastrointestinal symptoms accompanied by fever or chickenpox, (2) blood ammonia and / or serum transaminase (3) a sudden increase in central nervous system disorders, a change in consciousness (accompanied by other abnormalities), and (4) a decrease in prothrombin time and a significant increase in prothrombin time (<40% compared with the normal controls) Exclude other diseases with similar clinical features. According to Lovejoy grading scheme on children’s awareness status graded. 17