An effcient,rapid and facile procedure for conversion of aldoximes to nitriles using triphenylphosph

• 作 者: Ramin Ghorbani-Vaghei Lotf Shiri Arash Ghorbani-Choghamarani
• 机 构: Department of Organic Chemistry,Faculty of Chemistry,Bu-Ali Sina University,Department of Chemistry,
• 出 处: Chinese Chemical Letters
• 发表日期: 2013年12期
• 关键词: facile versatile have alkyl carboxylic phosphorus reagent esters aromatic packed

N,N,N0,N0-Tetrabromobenzene-1,3-disulfonamide(TBBDA)/triphenylphosphine and N,N,N0,N0-tetrachlorobenzene-1,3-disulfonamide(TCBDA)/triphenylphosphine have been introduced as highly effcient systems for the versatile conversion of aldoxime derivatives into nitriles.The process reported here is operationally simple and reactions have been mildly performed in dichloromethane at room temperature.

N, N, N0, N0-Tetrabromobenzene-1,3-disulfonamide (TBBDA) / triphenylphosphine and N, N, N0, N0- tetrachlorobenzene- 1,3-disulfonamide (TCBDA) / triphenylphosphine have been introduced as highly effcient systems for the versatile conversion of aldoxime derivatives into nitriles. The process reported here is operationally simple and reactions have been mildly performed in dichloromethane at room temperature.