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我们在研究肾上腺髓质素前体Ｎ端２０肽（ＰＡＭＰ）时，发现应用ＰＡＭＰ剂量在３０．０ｎｍｏｌ／ｋｇ时可引起大鼠心律失常发生率高达６４．７％。在５ｎｍｏｌ／ｋｇ时可明显增强肾上腺素（Ｅ）和去甲肾上腺素（ＮＥ）的致心律失常作用（未发表资料），而Ｅ也是升高血...
When we studied the adrenomedullin precursor N-terminal 20 peptide (PAMP), we found that the application of PAMP dose at 30.0nmol / kg can cause the incidence of arrhythmia in rats up to 64.7%. At 5nmol / kg can significantly enhance the epinephrine (E) and norepinephrine (NE) induced arrhythmia (unpublished data), while E is also elevated blood ...