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侵袭性真菌感染的诊断问题是影响治疗和预后的重要环节。临床实践中组织病理诊断仍是诊断的金标准,但组织病理诊断十分困难,常规检查方法培养和分泌物直接镜检阳性率低,污染和致病很难区分;影像学表现虽然没有特征性但具有重要的提示价值,特别是动态观察更有价值。真菌抗原成分的检测是有前途的辅助诊断手段,但敏感性和特异性仍需改进。在侵袭性真菌感染诊断中必须结合临床特征、影像资料和实验室检查及治疗后的动态观察综合判断。
The diagnosis of invasive fungal infection is an important part of the treatment and prognosis. Histopathological diagnosis in clinical practice is still the gold standard for diagnosis, but the diagnosis of histopathology is very difficult, routine examination of culture and secretions direct microscopy positive rate is low, pollution and pathogenicity is difficult to distinguish; imaging performance although there is no characteristic but Has important hint value, especially dynamic observation is more valuable. Detection of fungal antigen components is a promising adjuvant diagnostic tool, but the sensitivity and specificity still need to be improved. In the diagnosis of invasive fungal infection must be combined with clinical features, imaging data and laboratory tests and dynamic observation after comprehensive judgments.