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根据以往随机对照试验的分析,BCG预防麻风的效力为20～80%,产生这种明显效力差异的原因虽不完全清楚,但多半与各种地区因素(如宿主遗传学、皮肤色素沉着、日光接触、营养状况和致病菌株等)差异有关。然而,这些差异不能排除BCG在某些地区的实用性。作者在1979年小规模试验的基础上,从1980～1984年在马拉维北部的卡朗加地区对112,000人进行病例对照试验和队列分析,
According to previous randomized controlled trials, the efficacy of BCG in preventing leprosy is 20-80%. Although the reasons for this significant difference in efficacy are not completely understood, they are mostly related to various regional factors such as host genetics, skin pigmentation, Contact, nutritional status and pathogens, etc.). However, these differences do not preclude the practicality of BCG in some areas. Based on the small-scale trials conducted in 1979, the authors conducted case-control studies and cohort analyzes of 112,000 people in the Karanga region of northern Malawi from 1980 to 1984,